Autoimmune Diseases

There has been plenty of research correlating diseases such as ankylosing spondylitis, lupus, inflammatory bowel disease, and Behcet's syndrome (an autoimmune disease that causes inflammation of the blood vessels often causing blindness), and multiple sclerosis research suggests that increased intestinal permeability is closely involved in the inflammatory process that launches these and other autoimmune diseases and their related complications.

Dr Kenneth J. Finsand is of the opinion that mangosteen xanthones can and do affect the body in a positive way. It is important to heal the inflammatory process that takes place throughout the gut, but primarily in the small intestine. The small intestine is the second place after the stomach that becomes inflamed along the GI tract. It is in the small intestine that some of the most serious diseases begin.


Leaky gut syndrome

The increased permeability caused by inflammation of the mucosal or inner lining of the small intestine allows food particles to drop through the gut lining too quickly and thus causes the body to trigger what is referred to as coding.

Coding is a process by which the body attacks these foreign substances but misreads them and codes them as cells from different parts of the body such as the kidney cells.

The body's immune system attacks these misread cells and the autoimmune disease gets its first foothold on the body. Drinking mangosteen juice on a daily basis can in many cases help to reduce or eliminate this inflammatory process of the gut that leads to such things as lupus, MS, and rheumatoid arthritis. A deficiency in fatty acids can also aid in the inflammation process that can lead to an autoimmune disorder. Parasites and bacterial build-up can also result in an inflammatory situation that if left unchecked, will erode the inner lining of the small intestine and cause long-term autoimmune disorders. Research has shown that daily intake of mangosteen xanthones eradicates bacterial overload and eliminates parasites.


Bacterial and Viral Infections

Autoimmune diseases have also been linked to bacterial and viral infections. There is research showing bacteria linked to Lupus, MS, inflammatory bowel diseases, degenerative diseases, rheumatoid arthritis, and Scleroderma.

These health challenges have also been linked to genetic disposition of immune dysfunction where the mangosteen fruit is thought to help modulate the immune system, as well as being antibacterial, antifungal and antiviral.

Dr. Albert Miller,M.D. has done extensive research on mangosteen with respect to autoimmune diseases and actually increased his own bone density with mangosteen. It appears that these types of results however take a fairly significant amount of time to get desirable results. We have to remember that mangosteen is a fruit and a food, not a drug. People using natural supplementation should be prepared to make a commitment consistently and regularly over long periods of time for maximum benefit.

The role of Inflammation

Acute inflammation – the kind that protects and heals the body after an injury or infection – is essential and normal. In the wake of a nasty cut or broken bone, the battle is on! Immediately, a biochemical cascade improves blood flow to the area. Nerve endings and other cells at the site of the injury or infection send out signaling molecules and other chemical components to recruit the body's equivalent of the Superhero – white blood cells that fight off foreign bodies. It's an amazing process that from the surface looks like swelling and can hurt, but it's all part of making things better. That's acute inflammation. It's necessary and normal for good health.

The other kind – chronic inflammation, also known as low-grade or systemic inflammation – can play a more puzzling and long-lasting role in the body. Consider the vast array of autoimmune disorders, such as rheumatoid arthritis, lupus and polymyalgia rheumatic, where the body's immune system mistakenly initiates an inflammatory response even though there's no apparent inflammation to fight off. Chronic inflammation plays a more obvious role in diseases such as asthma and the inflammatory bowel diseases ulcerative colitis and Crohn's disease.

And what about the not-so-obvious role of chronic inflammation? Consider the possible connection between gum disease and cardiovascular disease. Research indicates that heart disease, clogged arteries, stroke and bacterial endocarditis may be linked to oral health. Although more study is needed to confirm this possible link, some scientists believe that bacteria from gum disease can enter the bloodstream and make its way to the heart.

Even less obvious, but of enormous interest to researchers, is the part inflammation plays in cancer. For instance, chronic bladder inflammation due to repeated urinary infections or cystitis may increase risk of a squamous cell bladder cancer. In some areas of the world, this type of cancer is linked to chronic inflammation caused by infection with a parasite.

Just what does all this mean for you? Can you actually do something to reduce your risk of chronic inflammation that may play a part in disease? 

What you can do is make a point to avoid certain things that cause inflammation and are proven unhealthy. Prime examples are smoking and excessive alcohol use.

Mangosteen (Garcinia Mangostana L.) is credited with anti-allergy, antibacterial, antifungal, antihistamine and anti-inflammatory qualities amongst many others. Numerous studies also indicate possible cancer-preventative qualities.


List of Auto-Immune Diseases A-Z

  • Acute disseminated encephalomyelitis (ADEM)
  • Addison's disease – also called adrenal insufficiency or hypocortisolism
  • Allergic granulomatosis and angiitis or Churg-Strauss syndrome (CSS)
  • Alopecia or Alopecia Areata (AA) 
  • Anklosing spondylitis 
  • Autoimmune chronic active hepatitis (CAH), or autoimmune hepatitis
  • Autoimmune hemolytic anemia   
  • Autoimmune pancreatitis (AIP) 
  • Autoimmune retinopathy (AR) see Retinopathy 
  • Autoimmune thrombocytopenic purpura 
  • Autoimmune neutropenia 
  • Autoimmune Inner Ear Disease (AIED) 
  • Antiphospholipid Syndrome (APS) 
  • Autoimmune Lymphoproliferative Syndrome (ALPS)
  • Behcet's syndrome 
  • Bullus pemphigoid 
  • Celiac disease 
  • Churg-Strauss Syndrome (CSS) or Allergic Granulomatosis Angiitis
  • Chronic bullous disease of childhood 
  • Chronic inflammatory demyelinating Polyradiculoneuropathy (CIDP) 
  • Cictricial  pemphigoid (CP) 
  • Central Nervous System Vasculitis 
  • Crohn's Disease 
  • Cryoglobulinemia
  • Dermatitis herpetiformis (DH) 
  • Discoid lupus erythematosus (DLE)
  • Encephalomyelitis 
  • Epidermolysis bullosa acquisita (EBA) 
  • Erythema nodosum
  • Evans syndrome 
  • Giant Cell Arteritis see Temporal arteritis
  • Graft-versus-host disease
  • Graves' Disease 
  • Gullain-Barre syndrome 
  • Hanot Syndrome see Primary biliary Cirrhosis
  • Hashimoto's thyroiditis also called autoimmune thyroiditis and chronic lymphocytic thyroiditis
  • Hypersensitivity Vasculitis (HV) or small vessel vasculitishas
  • Immune-mediated infertility 
  • Inflammatory bowel disease also called colitis, enteritis and ileitis.
  • Insulin-dependent diabetes mellitus 
  • Isolated vasculitis of the Central nervous system or CNS Vasculitis
  • Isaacs' Syndrome: Neuromyotonia 
  • Kawasaki disease (KD) 
  • Lambert-Eaton myasthenic syndrome (LEMS) 
  • Linear IgA disease 
  • Lupus – see Systemic lupus erythematosus  
  • Meniere's Disease 
  • Microscopic Polyangiitis (MPA)
  • Mixed connective tissue disease or MCTD
  • Monoclonal Gammopathy 
  • Myasthenia gravis  
  • Multiple Sclerosis  
  • Multifocal motor neuropathy 
  • Neuromyotonia or Isaac's syndrome 
  • Neutropenia see Autoimmune Neutropenia
  • Oophoritis 
  • Opsoclonus-myoclonus syndrome 
  • Orchitis 
  • Paraneoplastic neurologic disorders  
  • Pemphigus vulgaris causes 
  • Pemphigus follaceus PF) 
  • Pemphigoid gestationis
  • Pernicious anemia 
  • Paraneoplastic pemphigus (PNP) 
  • Polyangiitis - see Microscopic polyangiitis
  • Polyarteritis nodosa (PAN) 
  • Polymyositis/dermatomyositis 
  • Polymyalgia Rheumatica 
  • Primary biliary Cirrhosis (PBC)
  • Primary sclerosing cholangitis (PSC) 
  • Psoriasis  
  • Raynaud's
  • Recoverin-associated retinopathy (RAR) see Retinopathy 
  • Reactive Arthritis formerly known as Reiter’s syndrome
  • Retinopathy 
  • Rheumatoid arthritis (RA)
  • Sarcoidosis   
  • Sclerosing cholangitis – see Primary Sclerosing Cholangitis
  • Sjogren's syndrome 
  • Systemic necrotizing vascolitides
  • Stiff man syndrome or Moersch-Woltmann syndrome
  • Systemic lupus erythematosus 
  • Systemic sclerosis (scleroderma) 
  • Temporal arteritis or giant cell arteritis (GCV)
  • Takayasu's arteritis 
  • Thromboangiitis obliterans or Buerger's disease  
  • Thyroiditis with hypothyroidism
  • Thyroiditis with hyperthyroidism 
  • Type I autoimmune polyglandular syndrome (PAS)
  • Type II autoimmune polyglandular syndrome 
  • Vasculitis 
  • Wegener's granulomatosis 

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